Cardioprotective effects of Bassia indica via NF-κB and BCL-2/BAX modulation in isoproterenol-induced myocardial injury

BackgroundMyocardial infarction (MI) is a fatal coronary heart disease that develops due to prolonged hypoxia. During MI progression, uncontrolled inflammation and apoptosis mediated by NF-κB and BAX/BCL-2 signaling pathways potentiate cardiac injury. Phenolic and flavonoid-rich medicinal plants hav...

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Bibliographic Details
Published in:Frontiers in Pharmacology
Main Authors: Fayyaz Anjum, Saad Touqeer, QurratUlAin Jamil, Ayesha Rida, Esraa M. Haji, Sulaiman Mohammed Abdullah Alnasser, Ali F. Almutairy, Hajar Alghamdi, Ashfaq Ahmad, Shahid Muhammad Iqbal
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-10-01
Subjects:
Bassia indica
myocardial infarction
inflammation
apoptosis
anti-inflammatory
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1628715/full

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https://www.frontiersin.org/articles/10.3389/fphar.2025.1628715/full

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