Investigation of griffithsin's interactions with human cells confirms its outstanding safety and efficacy profile as a microbicide candidate.

Many natural product-derived lectins such as the red algal lectin griffithsin (GRFT) have potent in vitro activity against viruses that display dense clusters of oligomannose N-linked glycans (NLG) on their surface envelope glycoproteins. However, since oligomannose NLG are also found on some host p...

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الحاوية / القاعدة:	PLoS ONE
المؤلفون الرئيسيون:	Joseph Calvin Kouokam, Dana Huskens, Dominique Schols, Andrew Johannemann, Shonna K Riedell, Wendye Walter, Janice M Walker, Nobuyuki Matoba, Barry R O'Keefe, Kenneth E Palmer
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Public Library of Science (PLoS) 2011-01-01
الوصول للمادة أونلاين:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0022635&type=printable