Identification of small molecule activators of BMP signaling.

Bone Morphogenetic Proteins (BMPs) are morphogens that play a major role in regulating development and homeostasis. Although BMPs are used for the treatment of bone and kidney disorders, their clinical use is limited due to the supra-physiological doses required for therapeutic efficacy causing seve...

Full description

Bibliographic Details
Published in:PLoS ONE
Main Authors: Karen Vrijens, Wenwei Lin, Jimmy Cui, Dana Farmer, Jonathan Low, Elodie Pronier, Fu-Yue Zeng, Anang A Shelat, Kiplin Guy, Michael R Taylor, Taosheng Chen, Martine F Roussel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Online Access:http://europepmc.org/articles/PMC3602516?pdf=render

Internet

http://europepmc.org/articles/PMC3602516?pdf=render

Similar Items