Determination of mitomycin C in rat plasma by liquid chromatography-tandem mass spectrometry and its application for determining pharmacokinetics in rat
To develop the liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for measuring mitomycin C in rat plasma, samples were processed using solid-phase extraction, with the internal standard being carbamazepine. A reversed phased C18 column was utilized for the LC-MS/MS study, and mobile p...
| 發表在: | Heliyon |
|---|---|
| Main Authors: | , , , , |
| 格式: | Article |
| 語言: | 英语 |
| 出版: |
Elsevier
2024-06-01
|
| 主題: | |
| 在線閱讀: | http://www.sciencedirect.com/science/article/pii/S2405844024089588 |