Next-generation sequencing identifies CDKN2A alterations as prognostic biomarkers in recurrent or metastatic head and neck squamous cell carcinoma predominantly receiving immune checkpoint inhibitors

BackgroundThis study aimed to identify potential biomarkers in patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) and further probe the prognostic implications of CDKN2A mutations, particularly within a subset receiving immunotherapy.MethodsIn this retrospective sing...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Liqiong Xue, Wenbo Tang, Jiuli Zhou, Junli Xue, Qun Li, Xiaoxiao Ge, Fengjuan Lin, Wei Zhao, Ye Guo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-10-01
Subjects:	next-generation sequencing head and neck squamous cell carcinoma cyclin-dependent kinase inhibitor 2A prognosis immunotherapy
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2023.1276009/full