Drug Transporter Expression and Activity in Human Hepatoma HuH-7 Cells

Human hepatoma cells may represent a valuable alternative to the use of human hepatocytes for studying hepatic drug transporters, which is now a regulatory issue during drug development. In the present work, we have characterized hepatic drug transporter expression, activity and regulation in human...

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Bibliographic Details
Published in:Pharmaceutics
Main Authors: Elodie Jouan, Marc Le Vée, Claire Denizot, Yannick Parmentier, Olivier Fardel
Format: Article
Language:English
Published: MDPI AG 2016-12-01
Subjects:
hepatoma
hepatocytes
HuH-7
drug transporters
MRP2
Online Access:http://www.mdpi.com/1999-4923/9/1/3

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http://www.mdpi.com/1999-4923/9/1/3

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