Gallium Nitrate Enhances Antimicrobial Activity of Colistin against Klebsiella pneumoniae by Inducing Reactive Oxygen Species Accumulation

ABSTRACT Klebsiella pneumoniae, a pathogen of critical clinical concern, urgently demands effective therapeutic options owing to its drug resistance. Polymyxins are increasingly regarded as a last-line therapeutic option for the treatment of multidrug-resistant (MDR) Gram-negative bacterial infectio...

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Bibliographic Details

Published in:	Microbiology Spectrum
Main Authors:	Mingjuan Guo, Ping Tian, Qingqing Li, Bao Meng, Yuting Ding, Yanyan Liu, Yasheng Li, Liang Yu, Jiabin Li
Format:	Article
Language:	English
Published:	American Society for Microbiology 2023-08-01
Subjects:	gallium colistin Klebsiella pneumoniae reactive oxygen species bacterial antioxidant activity oxidative stress
Online Access:	https://journals.asm.org/doi/10.1128/spectrum.00334-23