IL-4 and IL-13 induce equivalent expression of traditional M2 markers and modulation of reactive oxygen species in human macrophages

Abstract In cardiovascular disease, pathological and protective roles are reported for the Th2 cytokines IL-4 and IL-13, respectively. We hypothesised that differential effects on macrophage function are responsible. Type I and II receptor subunit (IL-2Rγ, IL-4Rα and IL-13Rα1) and M2 marker (MRC-1,...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Tara E. Scott, Caitlin V. Lewis, Mingyu Zhu, Chao Wang, Chrishan S. Samuel, Grant R. Drummond, Barbara K. Kemp-Harper
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-11-01
Online Access:	https://doi.org/10.1038/s41598-023-46237-2