Cooperative interaction of interferon regulatory factor -1 and bromodomain—containing protein 4 on RNA polymerase activation for intrinsic innate immunity

IntroductionThe human orthopneumovirus, Respiratory Syncytial Virus (RSV), is the causative agent of severe lower respiratory tract infections (LRTI) and exacerbations of chronic lung diseases. In immune competent hosts, RSV productively infects highly differentiated epithelial cells, where it elici...

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出版年:	Frontiers in Immunology
主要な著者:	Xiaofang Xu, Dianhua Qiao, Allan R. Brasier
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2024-03-01
主題:	RSV transcriptional elongation RNA pol II small airway basal cells multipotent stem cell
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1366235/full