Novel approach to exploring protease activity and targets in HIV-associated obstructive lung disease using combined proteomic-peptidomic analysis

Abstract Background Obstructive lung disease (OLD) is increasingly prevalent among persons living with HIV (PLWH). However, the role of proteases in HIV-associated OLD remains unclear. Methods We combined proteomics and peptidomics to comprehensively characterize protease activities. We combined mas...

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Bibliographic Details

Published in:	Respiratory Research
Main Authors:	Sarah Samorodnitsky, Monica Kruk, Eric F. Lock, Ken M. Kunisaki, Alison Morris, Janice M. Leung, Danielle Weise, Subina Mehta, Laurie L. Parker, Pratik D. Jagtap, Timothy J. Griffin, Chris H. Wendt
Format:	Article
Language:	English
Published:	BMC 2024-09-01
Online Access:	https://doi.org/10.1186/s12931-024-02933-9