Application of metagenomic next-generation sequencing for rapid molecular identification in spinal infection diagnosis

ObjectiveThis study aimed to determine the sensitivity and specificity of metagenomic next−generation sequencing (mNGS) for detecting pathogens in spinal infections and to identify the differences in the diagnostic performance between mNGS and targeted next−generation sequencing (tNGS).MethodsA tota...

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Bibliographic Details

Published in:	Frontiers in Cellular and Infection Microbiology
Main Authors:	Hui Lv, Sheng Liao, Zhenzhen Shi, Yuan Guo, JianHong Zhou, Hui Chen, Fei Luo, JianZhong Xu, ZhongRong Zhang, ZeHua Zhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-07-01
Subjects:	spinal infection metagenomic next-generation sequencing targeted next-generation sequencing spinal tuberculosis sensitivity diagnosis
Online Access:	https://www.frontiersin.org/articles/10.3389/fcimb.2024.1382635/full