Anaplastic thyroid cancer cells reduce CD71 levels to increase iron overload tolerance

Abstract Background Follicular thyroid cancer (FTC) is a prevalent form of differentiated thyroid cancer, whereas anaplastic thyroid cancer (ATC) represents a rare, fast-growing, undifferentiated, and highly aggressive tumor, posing significant challenges for eradication. Ferroptosis, an iron-depend...

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Bibliographic Details
Published in:Journal of Translational Medicine
Main Authors: Simona D’Aprile, Simona Denaro, Anna Maria Pavone, Sebastiano Giallongo, Cesarina Giallongo, Alfio Distefano, Lucia Salvatorelli, Filippo Torrisi, Raffaella Giuffrida, Stefano Forte, Daniele Tibullo, Giovanni Li Volti, Gaetano Magro, Nunzio Vicario, Rosalba Parenti
Format: Article
Language:English
Published: BMC 2023-11-01
Subjects:
Thyroid cancer
CD71
Ferroptosis
Iron overload
Erastin
RSL3
Online Access:https://doi.org/10.1186/s12967-023-04664-9

Internet

https://doi.org/10.1186/s12967-023-04664-9

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