Modeling of Fabry disease nephropathy using patient derived human induced pluripotent stem cells and kidney organoid system

Abstract Objectives To explore the possibility of kidney organoids generated using patient derived human induced pluripotent stem cells (hiPSC) for modeling of Fabry disease nephropathy (FDN). Methods First, we generated hiPSC line using peripheral blood mononuclear cells (PBMCs) from two male FD-pa...

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Bibliographic Details

Published in:	Journal of Translational Medicine
Main Authors:	Sheng Cui, Xianying Fang, Hanbi Lee, Yoo Jin Shin, Eun-Sil Koh, Sungjin Chung, Hoon Suk Park, Sun Woo Lim, Kang In Lee, Jae Young Lee, Chul Woo Yang, Byung Ha Chung
Format:	Article
Language:	English
Published:	BMC 2023-02-01
Subjects:	Fabry disease hiPSC Kidney organoids Disease modeling
Online Access:	https://doi.org/10.1186/s12967-023-03992-0