Rapid Low-Cost Microarray-Based Genotyping for Genetic Screening in Primary Immunodeficiency

Background: Genetic tests for primary immunodeficiency disorders (PIDs) are expensive, time-consuming, and not easily accessible in developing countries. Therefore, we studied the feasibility of a customized single nucleotide variant (SNV) microarray that we developed to detect disease-causing varia...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Narissara Suratannon, Rogier T. A. van Wijck, Linda Broer, Laixi Xue, Joyce B. J. van Meurs, Barbara H. Barendregt, Mirjam van der Burg, Willem A. Dik, Pantipa Chatchatee, Anton W. Langerak, Sigrid M. A. Swagemakers, Jacqueline A. C. Goos, Irene M. J. Mathijssen, Virgil A. S. H. Dalm, Kanya Suphapeetiporn, Kim C. Heezen, Jose Drabwell, André G. Uitterlinden, Peter J. van der Spek, P. Martin van Hagen, The South East Asia Primary Immunodeficiencies (SEAPID) Consortium
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-04-01
Subjects:	primary immunodeficiencies microarray-based genotyping SNP microarray single nucleotide variants (SNV) calling copy number variants (CNV) calling
Online Access:	https://www.frontiersin.org/article/10.3389/fimmu.2020.00614/full