Generation of Transcript Length Variants and Reprogramming of mRNA Splicing During Atherosclerosis Progression in ApoE-Deficient Mice

<b>Background.</b> Variant 3′UTRs provide mRNAs with different binding sites for miRNAs or RNA-binding proteins (RBPs) allowing the establishment of new regulatory environments. Regulation of 3′UTR length impacts on the control of gene expression by regulating accessibility of miRNAs or...

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Bibliographic Details

Published in:	Biomedicines
Main Authors:	Miguel Hueso, Adrián Mallén, Estanis Navarro
Format:	Article
Language:	English
Published:	MDPI AG 2024-11-01
Subjects:	5′UTR/3′UTR lengthening alternative splicing signatures atherosclerosis mRNA isoform switching splicing reprogramming
Online Access:	https://www.mdpi.com/2227-9059/12/12/2703