Deconstructing the DGAT1 enzyme: membrane interactions at substrate binding sites.

Diacylglycerol acyltransferase 1 (DGAT1) is a key enzyme in the triacylglyceride synthesis pathway. Bovine DGAT1 is an endoplasmic reticulum membrane-bound protein associated with the regulation of fat content in milk and meat. The aim of this study was to evaluate the interaction of DGAT1 peptides...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Jose L S Lopes, Leila M Beltramini, Bonnie A Wallace, Ana P U Araujo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Online Access:https://doi.org/10.1371/journal.pone.0118407