Zebrafish chemical screening reveals the impairment of dopaminergic neuronal survival by cardiac glycosides.

Parkinson's disease is a neurodegenerative disorder characterized by the prominent degeneration of dopaminergic (DA) neurons among other cell types. Here we report a first chemical screen of over 5,000 compounds in zebrafish, aimed at identifying small molecule modulators of DA neuron developme...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Yaping Sun, Zhiqiang Dong, Hadie Khodabakhsh, Sandip Chatterjee, Su Guo
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Online Access:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0035645&type=printable