Clinical characterization and founder effect analysis in Chinese amyotrophic lateral sclerosis patients with SOD1 common variants

Objective In the Asian population, SOD1 variants are the most common cause of amyotrophic lateral sclerosis (ALS). To date, more than 200 variants have been reported in SOD1. This study aimed to summarize the genotype–phenotype correlation and determine whether the patients carrying common variants...

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Bibliographic Details

Published in:	Annals of Medicine
Main Authors:	Pei-Shan Wang, Xin-Xia Yang, Qiao Wei, Yong-Ting Lv, Zhi-Ying Wu, Hong-Fu Li
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2024-12-01
Subjects:	Amyotrophic lateral sclerosis SOD1 Chinese common variants founder effect SOD1 aggregation
Online Access:	https://www.tandfonline.com/doi/10.1080/07853890.2024.2407522