Causality of blood metabolites on hepatocellular carcinoma and cholangiocarcinoma: a metabolome-wide mendelian randomization study

Abstract Background Reportedly, there is an association between body metabolites and the risk of Hepatocellular Carcinoma (HCC) & Cholangiocarcinoma (CCA), possibly due to disrupted metabolic pathways leading to oxidative stress and an imbalance in cell proliferation and apoptosis, thereby incre...

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出版年:	BMC Cancer
主要な著者:	Lin Ning, Zhanhua Gao, Di Chen, Jie Han, Guanyue Xie, Jianguang Sun
フォーマット:	論文
言語:	英語
出版事項:	BMC 2025-03-01
主題:	Hepatocellular carcinoma Cholangiocarcinoma Metabolites Mendelian randomization Causal relationship
オンライン･アクセス:	https://doi.org/10.1186/s12885-025-13690-3