Donor KIR genotype based outcome prediction after allogeneic stem cell transplantation: no land in sight

Optimizing natural killer (NK) cell alloreactivity could further improve outcome after allogeneic hematopoietic cell transplantation (alloHCT). The donor’s Killer-cell Immunoglobulin-like Receptor (KIR) genotype may provide important information in this regard. In the past decade, different models h...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Johannes Schetelig, Henning Baldauf, Falk Heidenreich, Jorinde D. Hoogenboom, Stephen R. Spellman, Alexander Kulagin, Thomas Schroeder, Henrik Sengeloev, Peter Dreger, Edouard Forcade, Jan Vydra, Eva Maria Wagner-Drouet, Goda Choi, Shankara Paneesha, Nuno A. A. Miranda, Alina Tanase, Liesbeth C. de Wreede, Vinzenz Lange, Alexander H. Schmidt, Jürgen Sauter, Joshua A. Fein, Yung-Tsi Bolon, Meilun He, Steven G. E. Marsh, Shahinaz M. Gadalla, Sophie Paczesny, Annalisa Ruggeri, Christian Chabannon, Katharina Fleischhauer
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-04-01
Subjects:	killer-cell immunoglobulin-like receptor (KIR) allogeneic hematopoietic cell transplantation (alloHCT) risk of relapse donor selection prediction model
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1350470/full