Biodistribution of Intratracheal, Intranasal, and Intravenous Injections of Human Mesenchymal Stromal Cell-Derived Extracellular Vesicles in a Mouse Model for Drug Delivery Studies

Mesenchymal stromal cell-derived extracellular vesicles (MSC-EVs) are extensively studied as therapeutic tools. Evaluation of their biodistribution is fundamental to understanding MSC-EVs’ impact on target organs. In our work, MSC-EVs were initially labeled with DiR, a fluorescent lipophilic dye, an...

Full description

Bibliographic Details
Published in:Pharmaceutics
Main Authors: Anna Maria Tolomeo, Gaia Zuccolotto, Ricardo Malvicini, Giada De Lazzari, Alessandro Penna, Chiara Franco, Federico Caicci, Fabio Magarotto, Santina Quarta, Michela Pozzobon, Antonio Rosato, Maurizio Muraca, Federica Collino
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Subjects:
extracellular vesicles
biodistribution
pharmacokinetics
drug delivery
Online Access:https://www.mdpi.com/1999-4923/15/2/548

Internet

https://www.mdpi.com/1999-4923/15/2/548

Similar Items