RSL3 induces ferroptosis by activating the NF-κB signalling pathway to enhance the chemosensitivity of triple-negative breast cancer cells to paclitaxel

Abstract Chemotherapy resistance in triple-negative breast cancer (TNBC) leads to poor therapeutic effects and a poor prognosis. Given that paclitaxel-based chemotherapy is the main treatment method for TNBC, enhancing its chemosensitivity has been a research focus. Induced ferroptosis of tumour cel...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Jialin Yuan, Cong Liu, Chengwei Jiang, Ning Liu, Zhaoying Yang, Hua Xing
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-01-01
Subjects:	Triple-negative breast cancer Ferroptosis Chemosensitivity
Online Access:	https://doi.org/10.1038/s41598-025-85774-w