Epigenetic modifications: Key players in cancer heterogeneity and drug resistance

Cancer heterogeneity and drug resistance remain pivotal obstacles in effective cancer treatment and management. One major contributor to these challenges is epigenetic modifications - gene regulation that does not involve changes to the DNA sequence itself but significantly impacts gene expression....

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Bibliographic Details

Published in:	Translational Oncology
Main Authors:	Hana Q. Sadida, Alanoud Abdulla, Sara Al Marzooqi, Sheema Hashem, Muzafar A. Macha, Ammira S. Al-Shabeeb Akil, Ajaz A. Bhat
Format:	Article
Language:	English
Published:	Elsevier 2024-01-01
Subjects:	Epigenetic modifications Cancer heterogeneity Drug resistance DNA methylation Histone modifications Chromatin remodeling
Online Access:	http://www.sciencedirect.com/science/article/pii/S1936523323002073