The Effect of Autophagy on Chronic Intermittent Hypobaric Hypoxia Ameliorating Liver Damage in Metabolic Syndrome Rats

AimOur previous study demonstrated that chronic intermittent hypobaric hypoxia (CIHH) can confer hepatic protection by reducing endoplasmic reticulum stress (ERS) in high-fat-high-fructose induced metabolic syndrome (MS) rats. It is known that there is a functional coupling between autophagy and ERS...

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Bibliographic Details

Published in:	Frontiers in Physiology
Main Authors:	Fang Cui, Hao Fei Hu, Jing Guo, Jie Sun, Min Shi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-01-01
Subjects:	chronic intermittent hypobaric hypoxia metabolic syndrome endoplasmic reticulum stress autophagy AMPK-mTOR signaling pathway
Online Access:	https://www.frontiersin.org/article/10.3389/fphys.2020.00013/full