Targeting PHB2-mediated mitophagy alleviates nonesterified fatty acid-induced mitochondrial dysfunction in bovine mammary epithelial cells

ABSTRACT: Mitochondrial dysfunction has been reported to occur in the mammary gland of dairy cows suffering from ketosis. Prohibitin 2 (PHB2) plays a crucial role in regulating mitophagy, which clears impaired mitochondria to maintain normal mitochondrial function. Therefore, the current study aimed...

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Bibliographic Details

Published in:	Journal of Dairy Science
Main Authors:	Guojin Li, Liguang Cao, Kai Liu, Yifei Dong, Zifeng Yang, Jianchun Luo, Wenrui Gao, Lin Lei, Yuxiang Song, Xiliang Du, Xinwei Li, Wenwen Gao, Guowen Liu
Format:	Article
Language:	English
Published:	Elsevier 2024-10-01
Subjects:	clinical ketosis prohibitin 2 mitophagy mitochondrial dysfunction
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022030224009214