DST-3, a Novel Modified Cryptotanshinone, Protects Against Pulmonary Fibrosis via Inhibiting STAT3/Smad Signaling Pathway and Improves Bioavailability

<b>Background/Objectives</b>: Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease characterized by progressive loss of lung function and poor prognosis. Cryptotanshinone (CTS), a small-molecule compound extracted from Salvia miltiorrhiza, possesses diverse pharmacological activit...

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Bibliographic Details

Published in:	Pharmaceutics
Main Authors:	Ruoqing Guan, Xiangjun He, Yuxing Dai, Guangye Huang, Zhaoyun Xue, Jianwen Chen, Peiqing Liu
Format:	Article
Language:	English
Published:	MDPI AG 2025-10-01
Subjects:	DST-3 pulmonary fibrosis pharmacokinetics HPLC tandem mass spectrometry cryptotanshinone
Online Access:	https://www.mdpi.com/1999-4923/17/10/1307