Single-cell RNA sequencing in cancer research: discovering novel biomarkers and therapeutic targets for immune checkpoint blockade

Abstract Immune checkpoint blockade (ICB) has become a promising strategy in treating advanced cancers, providing significant survival benefits for patients with various cancer types. However, among the vast population of cancer patients, only a small fraction are able to respond to and derive benef...

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Bibliographic Details

Published in:	Cancer Cell International
Main Authors:	Boyu Sun, Ziyu Xun, Nan Zhang, Kai Liu, Xiangqi Chen, Haitao Zhao
Format:	Article
Language:	English
Published:	BMC 2023-12-01
Subjects:	Immune checkpoint blockade Single-cell RNA sequencing Tumor microenvironment Biomarker Therapeutic target
Online Access:	https://doi.org/10.1186/s12935-023-03158-4