Treatment-related hemophagocytic lymphohistiocytosis due to atezolizumab: a case report and review of the literature

Abstract Background Immune checkpoint inhibitors avoid inhibition of T-cell responses, upregulating antitumor immune response. Moreover, a dysregulation with hyperactive immune response can be caused, some of them underdiagnosed. Hemophagocytic lymphohistiocytosis is a rare and often fatal syndrome...

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Bibliographic Details

Published in:	Journal of Medical Case Reports
Main Authors:	Jaime Rubio-Perez, Ángel Ricardo Rodríguez-Perez, María Díaz-Blázquez, Victor Moreno-García, Manuel Dómine-Gómez
Format:	Article
Language:	English
Published:	BMC 2022-10-01
Subjects:	HLH IrAE Pharmacovigiliance ICI
Online Access:	https://doi.org/10.1186/s13256-022-03585-3