A Selective Inhibitor of Cardiac Troponin I Phosphorylation by Delta Protein Kinase C (δPKC) as a Treatment for Ischemia-Reperfusion Injury

Myocardial infarction is the leading cause of cardiovascular mortality, with myocardial injury occurring during ischemia and subsequent reperfusion (IR). We previously showed that the inhibition of protein kinase C delta (δPKC) with a pan-inhibitor (δV1-1) mitigates myocardial injury and improves mi...

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Bibliographic Details

Published in:	Pharmaceuticals
Main Authors:	Nir Qvit, Amanda J. Lin, Aly Elezaby, Nicolai P. Ostberg, Juliane C. Campos, Julio C. B. Ferreira, Daria Mochly-Rosen
Format:	Article
Language:	English
Published:	MDPI AG 2022-02-01
Subjects:	cardiac troponin I cardiac ischemia-reperfusion injury peptides
Online Access:	https://www.mdpi.com/1424-8247/15/3/271