Exosomal circ-BRWD1 contributes to osteoarthritis development through the modulation of miR-1277/TRAF6 axis

Abstract Background Circular RNAs (circRNAs) can act as vital players in osteoarthritis (OA). However, the roles of circRNAs in OA remain obscure. Herein, we explored the roles of exosomal circRNA bromodomain and WD repeat domain containing 1(circ-BRWD1) in OA pathology. Methods In vitro model of OA...

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Bibliographic Details

Published in:	Arthritis Research & Therapy
Main Authors:	Zhenye Guo, Huan Wang, Feng Zhao, Min Liu, Feida Wang, Mingming Kang, Weifu He, Zhi Lv
Format:	Article
Language:	English
Published:	BMC 2021-06-01
Subjects:	OA Exosome Circ-BRWD1 MiR-1277 TRAF6
Online Access:	https://doi.org/10.1186/s13075-021-02541-8