Effectiveness and Clinical Indications of 2 × 4 Fixed Orthodontic Therapy in Regard to Mixed Dentition: A Systematic Review

Background/Objectives: This systematic review examines the effectiveness and clinical indications of the 2 × 4 fixed orthodontic appliance for interceptive treatment in children with mixed dentition, aiming to simplify future orthodontic needs. Methods: Following the PRISMA guidelines, a search was...

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Bibliographic Details

Published in:	Children
Main Authors:	Gianna Dipalma, Grazia Marinelli, Lucia Casamassima, Paola Nardelli, Danilo Ciccarese, Paolo De Sena, Francesco Inchingolo, Vito Crincoli, Andrea Palermo, Ioana Roxana Bordea, Andrea Carbonara, Angelo Michele Inchingolo, Alessio Danilo Inchingolo
Format:	Article
Language:	English
Published:	MDPI AG 2025-07-01
Subjects:	mixed dentition early mixed dentition 2 × 4 appliance fixed appliance orthodontic brackets interceptive orthodontic treatment
Online Access:	https://www.mdpi.com/2227-9067/12/7/897