The ability of flux balance analysis to predict evolution of central metabolism scales with the initial distance to the optimum.
The most powerful genome-scale framework to model metabolism, flux balance analysis (FBA), is an evolutionary optimality model. It hypothesizes selection upon a proposed optimality criterion in order to predict the set of internal fluxes that would maximize fitness. Here we present a direct test of...
| الحاوية / القاعدة: | PLoS Computational Biology |
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| المؤلفون الرئيسيون: | , , , , |
| التنسيق: | مقال |
| اللغة: | الإنجليزية |
| منشور في: |
Public Library of Science (PLoS)
2013-01-01
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| الوصول للمادة أونلاين: | http://europepmc.org/articles/PMC3688462?pdf=render |