Chronic nicotine improves cognitive and social impairment in mice overexpressing wild type α-synuclein

In addition to dopaminergic and motor deficits, patients with Parkinson's disease (PD) suffer from non-motor symptoms, including early cognitive and social impairment, that do not respond well to dopaminergic therapy. Cholinergic deficits may contribute to these problems, but cholinesterase inh...

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Bibliographic Details

Published in:	Neurobiology of Disease
Main Authors:	Sudhakar R. Subramaniam, Iddo Magen, Nicholas Bove, Chunni Zhu, Vincent Lemesre, Garima Dutta, Chris Jean Elias, Henry A. Lester, Marie-Francoise Chesselet
Format:	Article
Language:	English
Published:	Elsevier 2018-09-01
Subjects:	Parkinson's disease Mouse model α-synuclein Nicotine Motor deficits Cognitive deficits
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996118301566