Immune cell population dynamics following neonatal BCG vaccination and aerosol BCG revaccination in rhesus macaques

Abstract The BCG vaccine is given to millions of children globally but efficacy wanes over time and differences in the immune systems between infants and adults can influence vaccine efficacy. To this end, 34 rhesus macaques were vaccinated with BCG within seven days of birth and blood samples were...

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Bibliographic Details
Published in:Scientific Reports
Main Authors: Laura Sibley, Charlotte Sarfas, Alexandra L. Morrison, Jessica Williams, Konstantinos Gkolfinos, Adam Mabbutt, William Eckworth, Steve Lawrence, Mike Dennis, Andrew White, Sally Sharpe
Format: Article
Language:English
Published: Nature Portfolio 2024-07-01
Online Access:https://doi.org/10.1038/s41598-024-67861-6