The Instability of Dimeric Fc-Fusions Expressed in Plants Can Be Solved by Monomeric Fc Technology

The potential therapeutic value of many proteins is ultimately limited by their rapid in vivo clearance. One strategy to limit clearance by metabolism and excretion, and improving the stability of therapeutic proteins, is their fusion to the immunoglobulin fragment crystallizable region (Fc). The Fc...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Frontiers in Plant Science
المؤلفون الرئيسيون: Pia Gattinger, Shiva Izadi, Clemens Grünwald-Gruber, Somanath Kallolimath, Alexandra Castilho
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Frontiers Media S.A. 2021-07-01
الموضوعات:
Nicotiana benthamiana
Fc-fusion proteins
EPO-Fc
protein instability
protein linkers
الوصول للمادة أونلاين:https://www.frontiersin.org/articles/10.3389/fpls.2021.671728/full

الانترنت

https://www.frontiersin.org/articles/10.3389/fpls.2021.671728/full

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