Hypomethylation of PlncRNA-1 promoter enhances bladder cancer progression through the miR-136-5p/Smad3 axis

Abstract Apart from being potential prognostic biomarkers and therapeutic targets, long non-coding RNAs (lncRNAs) modulate the development and progression of multiple cancers. PlncRNA-1 is a newly discovered lncRNA that exhibits the above properties through multiple regulatory pathways. However, the...

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Bibliographic Details
Published in:Cell Death and Disease
Main Authors: Weiting Kang, Qiang Wang, Yun Dai, Hanbo Wang, Muwen Wang, Jin Wang, Dong Zhang, Peng Sun, Taiguo Qi, Xunbo Jin, Zilian Cui
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Online Access:https://doi.org/10.1038/s41419-020-03240-z