Differential inhibitory effects of endocannabinoids on neuronal firing of mouse meningeal afferents

Abstract Background Increasing endocannabinoids (endoCBs), anandamide (AEA) and 2-arachidonoylglycerol (2-AG), through inhibition of the degrading hydrolase enzymes, fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL), respectively, has been proposed as approach to alleviate migrain...

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Bibliographic Details
Published in:The Journal of Headache and Pain
Main Authors: Georgii Krivoshein, Adriana Della Pietra, Juha Savinainen, Arn M. J. M. van den Maagdenberg, Rashid Giniatullin
Format: Article
Language:English
Published: BMC 2025-05-01
Subjects:
Migraine
Neuronal firing
Anandamide
2-arachidonoylglycerol
FAAH
MAGL
Online Access:https://doi.org/10.1186/s10194-025-02041-z

Internet

https://doi.org/10.1186/s10194-025-02041-z

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