Activation of the connective tissue growth factor (CTGF)-transforming growth factor β 1 (TGF-β 1) axis in hepatitis C virus-expressing hepatocytes.

BACKGROUND:The pro-fibrogenic cytokine connective tissue growth factor (CTGF) plays an important role in the development and progression of fibrosis in many organ systems, including liver. However, its role in the pathogenesis of hepatitis C virus (HCV)-induced liver fibrosis remains unclear. METHOD...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	PLoS ONE
المؤلفون الرئيسيون:	Tirumuru Nagaraja, Li Chen, Anuradha Balasubramanian, Jerome E Groopman, Kalpana Ghoshal, Samson T Jacob, Andrew Leask, David R Brigstock, Appakkudal R Anand, Ramesh K Ganju
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Public Library of Science (PLoS) 2012-01-01
الوصول للمادة أونلاين:	http://europepmc.org/articles/PMC3464290?pdf=render