Primary Cilia Formation Does Not Rely on WNT/β-Catenin Signaling

Primary cilia act as crucial regulators of embryo development and tissue homeostasis. They are instrumental for modulation of several signaling pathways, including Hedgehog, WNT, and TGF-β. However, gaps exist in our understanding of how cilia formation and function is regulated. Recent work has imp...

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Bibliographic Details

Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Ondrej Bernatik, Petra Paclikova, Anna Kotrbova, Vitezslav Bryja, Lukas Cajanek
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-02-01
Subjects:	primary cilia Wnt/β-catenin ciliogenesis cell signaling Wnt3a RPE-1
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2021.623753/full