Mutant ANP induces mitochondrial and ion channel remodeling in a human iPSC–derived atrial fibrillation model

Human induced pluripotent stem cell–derived cardiomyocytes (iPSC-CMs) can model heritable arrhythmias to personalize therapies for individual patients. Although atrial fibrillation (AF) is a leading cause of cardiovascular morbidity and mortality, current platforms to generate iPSC-atrial (a) CMs ar...

詳細記述

書誌詳細

出版年:	JCI Insight
主要な著者:	Olivia T. Ly, Hanna Chen, Grace E. Brown, Liang Hong, Xinge Wang, Yong Duk Han, Mahmud Arif Pavel, Arvind Sridhar, Mark Maienschein-Cline, Brandon Chalazan, Sang-Ging Ong, Khaled Abdelhady, Malek Massad, Lona Ernst Rizkallah, Jalees Rehman, Salman R. Khetani, Dawood Darbar
フォーマット:	論文
言語:	英語
出版事項:	American Society for Clinical investigation 2022-04-01
主題:	Cardiology Genetics
オンライン･アクセス:	https://doi.org/10.1172/jci.insight.155640