Exosomes from umbilical cord mesenchymal stem cells ameliorate intervertebral disc degeneration via repairing mitochondrial dysfunction

Background: Reactive oxygen species (ROS), predominantly generated by mitochondria, play a crucial role in the pathogenesis of intervertebral disc degeneration (IVDD). Reduction of ROS levels may be an effective strategy to delay IVDD. In this study, we assessed whether umbilical cord mesenchymal st...

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Bibliographic Details

Published in:	Journal of Orthopaedic Translation
Main Authors:	Shu Jia, Tao Yang, Sheng Gao, Luyue Bai, Zhiguo Zhu, Siqi Zhao, Yexin Wang, Xiao Liang, Yanpeng Li, Longfei Gao, Zifang Zhang, Xu Gao, Dongru Li, Shang Chen, Bin Zhang, Chunyang Meng
Format:	Article
Language:	English
Published:	Elsevier 2024-05-01
Subjects:	Umbilical cord mesenchymal stem cells Exosomes Mitochondrion Intervertebral disc degeneration
Online Access:	http://www.sciencedirect.com/science/article/pii/S2214031X23000785