Therapeutic Targeting of Cancer Stem Cells in Human Glioblastoma by Manipulating the Renin-Angiotensin System

Patients with glioblastoma (GB), a highly aggressive brain tumor, have a median survival of 14.6 months following neurosurgical resection and adjuvant chemoradiotherapy. Quiescent GB cancer stem cells (CSCs) invariably cause local recurrence. These GB CSCs can be identified by embryonic stem cell ma...

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發表在:	Cells
Main Authors:	David CH Tan, Imogen M Roth, Agadha C Wickremesekera, Paul F Davis, Andrew H Kaye, Theo Mantamadiotis, Stanley S Stylli, Swee T Tan
格式:	Article
語言:	英语
出版:	MDPI AG 2019-10-01
主題:	glioblastoma renin-angiotensin system cancer stem cells drug repurposing
在線閱讀:	https://www.mdpi.com/2073-4409/8/11/1364