Population size influences the type of nucleotide variations in humans

Abstract Background It is well known that the effective size of a population (N e ) is one of the major determinants of the amount of genetic variation within the population. However, it is unclear whether the types of genetic variations are also dictated by the effective population size. To examine...

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Bibliographic Details

Published in:	BMC Genetics
Main Author:	Sankar Subramanian
Format:	Article
Language:	English
Published:	BMC 2019-12-01
Subjects:	Type of nucleotide change Biased gene conversion Recombination Common and rare variants Deleterious variants Population bottleneck and human genomes
Online Access:	https://doi.org/10.1186/s12863-019-0798-9