Subversion of innate defenses by the interplay between DENV and pre-existing enhancing antibodies: TLRs signaling collapse.

<h4>Background</h4>The phenomenon of antibody dependent enhancement as a major determinant that exacerbates disease severity in DENV infections is well accepted. While the detailed mechanism of antibody enhanced disease severity is unclear, evidence suggests that it is associated with bo...

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Bibliographic Details

Published in:	PLoS Neglected Tropical Diseases
Main Authors:	Naphak Modhiran, Siripen Kalayanarooj, Sukathida Ubol
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2010-12-01
Online Access:	https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0000924&type=printable