Subversion of innate defenses by the interplay between DENV and pre-existing enhancing antibodies: TLRs signaling collapse.

<h4>Background</h4>The phenomenon of antibody dependent enhancement as a major determinant that exacerbates disease severity in DENV infections is well accepted. While the detailed mechanism of antibody enhanced disease severity is unclear, evidence suggests that it is associated with bo...

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發表在:PLoS Neglected Tropical Diseases
Main Authors: Naphak Modhiran, Siripen Kalayanarooj, Sukathida Ubol
格式: Article
語言:英语
出版: Public Library of Science (PLoS) 2010-12-01
在線閱讀:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0000924&type=printable