Subversion of innate defenses by the interplay between DENV and pre-existing enhancing antibodies: TLRs signaling collapse.
<h4>Background</h4>The phenomenon of antibody dependent enhancement as a major determinant that exacerbates disease severity in DENV infections is well accepted. While the detailed mechanism of antibody enhanced disease severity is unclear, evidence suggests that it is associated with bo...
| Published in: | PLoS Neglected Tropical Diseases |
|---|---|
| Main Authors: | Naphak Modhiran, Siripen Kalayanarooj, Sukathida Ubol |
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2010-12-01
|
| Online Access: | https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0000924&type=printable |
Similar Items
Transcriptomic analysis of DENV-2-infected human dermal fibroblasts identified potential mechanisms that suppressed ZIKV replication during sequential coinfection
by: Chernkhwan Kaofai, et al.
Published: (2025-05-01)
by: Chernkhwan Kaofai, et al.
Published: (2025-05-01)
Dengue: An Emerging Health Challenge ?
by: Sukathida Ubol
Published: (2007-07-01)
by: Sukathida Ubol
Published: (2007-07-01)
TLRs, Treg and B cells, an interplay of regulation during helminth infection
by: Laura E Layland, et al.
Published: (2012-02-01)
by: Laura E Layland, et al.
Published: (2012-02-01)
Anti-DENV-ED3 antibody cross-talks generate immune interference among the four DENVs
by: Md. Din Islam, et al.
Published: (2024-12-01)
by: Md. Din Islam, et al.
Published: (2024-12-01)
Subversion of Host Innate Immunity by Human Papillomavirus Oncoproteins
by: Irene Lo Cigno, et al.
Published: (2020-04-01)
by: Irene Lo Cigno, et al.
Published: (2020-04-01)
Subversion of Host Innate Immunity by Uropathogenic Escherichia coli
by: Patrick D. Olson, et al.
Published: (2016-01-01)
by: Patrick D. Olson, et al.
Published: (2016-01-01)
Differential Production of Midkine and Pleiotrophin by Innate APCs upon Stimulation through Nucleic Acid-Sensing TLRs
by: Elias A. Said, et al.
Published: (2023-01-01)
by: Elias A. Said, et al.
Published: (2023-01-01)
DENV-specific IgA contributes protective and non-pathologic function during antibody-dependent enhancement of DENV infection.
by: Adam D Wegman, et al.
Published: (2023-08-01)
by: Adam D Wegman, et al.
Published: (2023-08-01)
The Innate Immune Response in DENV- and CHIKV-Infected Placentas and the Consequences for the Fetuses: A Minireview
by: Felipe de Andrade Vieira Alves, et al.
Published: (2023-09-01)
by: Felipe de Andrade Vieira Alves, et al.
Published: (2023-09-01)
TLRs in Hepatic Cellular Crosstalk
by: Amelie E. Bigorgne, et al.
Published: (2010-01-01)
by: Amelie E. Bigorgne, et al.
Published: (2010-01-01)
TLRs, Alcohol, HCV, and Tumorigenesis
by: Keigo Machida
Published: (2010-01-01)
by: Keigo Machida
Published: (2010-01-01)
Of Flies and Men—The Discovery of TLRs
by: Hauke Johannes Weiss, et al.
Published: (2022-10-01)
by: Hauke Johannes Weiss, et al.
Published: (2022-10-01)
Role of Microglia TLRs in Neurodegeneration
by: Bernd L. Fiebich, et al.
Published: (2018-10-01)
by: Bernd L. Fiebich, et al.
Published: (2018-10-01)
Innate Immune Activation and Subversion of Mammalian Functions by Leishmania Lipophosphoglycan
by: Luis H. Franco, et al.
Published: (2012-01-01)
by: Luis H. Franco, et al.
Published: (2012-01-01)
THE ROLE OF INNATE IMMUNITY RECEPTORS (TLRs) IN MAINTAINING THE HOMEOSTASIS OF THE FEMALE GENITAL TRACT IN DEVELOPING PREGNANCY AND INTRAUTERINE INFECTION
by: A. V. Karaulov, et al.
Published: (2018-11-01)
by: A. V. Karaulov, et al.
Published: (2018-11-01)
Holding the Inflammatory System in Check: TLRs and NLRs
by: Eda K. Holl, et al.
Published: (2016-01-01)
by: Eda K. Holl, et al.
Published: (2016-01-01)
Recent Advances in DENV Receptors
by: Shuyu Fang, et al.
Published: (2013-01-01)
by: Shuyu Fang, et al.
Published: (2013-01-01)
Conventional and antibody-enhanced DENV infection of human macrophages induces differential immunotranscriptomic profiles
by: Céline S. C. Hardy, et al.
Published: (2025-03-01)
by: Céline S. C. Hardy, et al.
Published: (2025-03-01)
Balance of neutralizing Antibodies and Antibody Dependent Enhancement (ADE) In Dengue Virus (DENV) infection: a literature review
by: Regita Aulia Rosalina, et al.
Published: (2024-12-01)
by: Regita Aulia Rosalina, et al.
Published: (2024-12-01)
The role of toll-like receptors (TLRs) in pan-cancer
by: Runzhi Huang, et al.
Published: (2022-12-01)
by: Runzhi Huang, et al.
Published: (2022-12-01)
Toll-like receptors (TLRs) in the trained immunity era
by: Lena Alexopoulou, et al.
Published: (2025-09-01)
by: Lena Alexopoulou, et al.
Published: (2025-09-01)
TLRs, NF-κB, JNK, and Liver Regeneration
by: Yuji Iimuro, et al.
Published: (2010-01-01)
by: Yuji Iimuro, et al.
Published: (2010-01-01)
Exosomes: Potential Therapies for Disease via Regulating TLRs
by: Hong-Yan Guo, et al.
Published: (2020-01-01)
by: Hong-Yan Guo, et al.
Published: (2020-01-01)
Synucleinopathies Take Their Toll: Are TLRs a Way to Go?
by: Gabriella M. Mazzotta, et al.
Published: (2023-04-01)
by: Gabriella M. Mazzotta, et al.
Published: (2023-04-01)
Editorial: Ligands, Adaptors and Pathways of TLRs in Non-mammals
by: Jianguo Su, et al.
Published: (2019-10-01)
by: Jianguo Su, et al.
Published: (2019-10-01)
Shigella-mediated immunosuppression in the human gut: subversion extends from innate to adaptive immune responses
by: Katja Brunner, et al.
Published: (2019-06-01)
by: Katja Brunner, et al.
Published: (2019-06-01)
Structural basis of differential neutralization of DENV-1 genotypes by an antibody that recognizes a cryptic epitope.
by: S Kyle Austin, et al.
Published: (2012-01-01)
by: S Kyle Austin, et al.
Published: (2012-01-01)
Retracted: Recent Advances in DENV Receptors
by: The Scientific World Journal
Published: (2013-01-01)
by: The Scientific World Journal
Published: (2013-01-01)
基于DENV-prM/E基因构建DENV-VLP及其免疫学特性
Published: (2014-01-01)
Published: (2014-01-01)
Holding the Inflammatory System in Check: TLRs and Their Targeted Therapy in Asthma
by: Zhiyong Dong, et al.
Published: (2016-01-01)
by: Zhiyong Dong, et al.
Published: (2016-01-01)
TLRs in COVID-19: How they drive immunopathology and the rationale for modulation
by: F. Linzee Mabrey, et al.
Published: (2021-10-01)
by: F. Linzee Mabrey, et al.
Published: (2021-10-01)
Adaptive Evolution of Toll-Like Receptors (TLRs) in the Family Suidae.
by: Kwame A Darfour-Oduro, et al.
Published: (2015-01-01)
by: Kwame A Darfour-Oduro, et al.
Published: (2015-01-01)
MMP2 and TLRs modulate immune responses in the tumor microenvironment
by: Luciana R. Muniz-Bongers, et al.
Published: (2021-06-01)
by: Luciana R. Muniz-Bongers, et al.
Published: (2021-06-01)
Comparative monocyte and T cell responses in DENV-exposed subjects from South-East Asia and DENV-naïve residents in Taiwan
by: Sheng-Hsuan Wang, et al.
Published: (2025-02-01)
by: Sheng-Hsuan Wang, et al.
Published: (2025-02-01)
The interplay between innate lymphoid cells and microbiota
by: Rui Wang, et al.
Published: (2023-08-01)
by: Rui Wang, et al.
Published: (2023-08-01)
RNF115 Inhibits the Post‐ER Trafficking of TLRs and TLRs‐Mediated Immune Responses by Catalyzing K11‐Linked Ubiquitination of RAB1A and RAB13
by: Zhi‐Dong Zhang, et al.
Published: (2022-05-01)
by: Zhi‐Dong Zhang, et al.
Published: (2022-05-01)
Innate Immune Pathways in Host Defense
by: Thirumala-Devi Kanneganti, et al.
Published: (2012-01-01)
by: Thirumala-Devi Kanneganti, et al.
Published: (2012-01-01)
The Innate Defense in the Zika-Infected Placenta
by: Laíza Vianna Arruda, et al.
Published: (2022-11-01)
by: Laíza Vianna Arruda, et al.
Published: (2022-11-01)
Global Dynamics of Secondary DENV Infection with Diffusion
by: A. M. Elaiw, et al.
Published: (2021-01-01)
by: A. M. Elaiw, et al.
Published: (2021-01-01)
Q63, a novel DENV2 RdRp non-nucleoside inhibitor, inhibited DENV2 replication and infection
by: Xingang Yao, et al.
Published: (2018-12-01)
by: Xingang Yao, et al.
Published: (2018-12-01)
Similar Items
-
Transcriptomic analysis of DENV-2-infected human dermal fibroblasts identified potential mechanisms that suppressed ZIKV replication during sequential coinfection
by: Chernkhwan Kaofai, et al.
Published: (2025-05-01) -
Dengue: An Emerging Health Challenge ?
by: Sukathida Ubol
Published: (2007-07-01) -
TLRs, Treg and B cells, an interplay of regulation during helminth infection
by: Laura E Layland, et al.
Published: (2012-02-01) -
Anti-DENV-ED3 antibody cross-talks generate immune interference among the four DENVs
by: Md. Din Islam, et al.
Published: (2024-12-01) -
Subversion of Host Innate Immunity by Human Papillomavirus Oncoproteins
by: Irene Lo Cigno, et al.
Published: (2020-04-01)
