DETERMINATION OF IGG1 AND IGG3 SUBCLASSES OF RED BLOOD CELL ANTIBODIES: AN IMPORTANT TOOL FOR PREDICTING IMMUNE MEDIATED HEMOLYTISIS

Objectives: Red blood cell (RBC) antibodies of the IgG class can lead to hemolysis in patients depending on many factors, including the IgG subclass. IgGs, particularly IgG1 and IgG3-coated RBCs (red blood cells) are quickly recognized for phagocytosis leading to a greater potential for RBC destruct...

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Bibliographic Details
Published in:Hematology, Transfusion and Cell Therapy
Main Authors: RA Cardoso, TF Vieira, MCAV Conrado, FJ Luz, CK Kanashiro, MM Yoshisaki, A Reggiani, A Mendroni-Junior, V Rocha, CL Dinardo
Format: Article
Language:English
Published: Elsevier 2024-10-01
Online Access:http://www.sciencedirect.com/science/article/pii/S2531137924017140