Characterization of YKL-40 Binding to Extracellular Matrix Glycosaminoglycans

YKL-40 is a chitinase-like glycoprotein implicated in various pathological processes, yet its glycosaminoglycan (GAG) binding profile beyond heparin has not been examined. In this study, we performed a Microscale Thermophoresis (MST) analysis on the heparin-binding glycoprotein YKL-40 using low mole...

Full description

Bibliographic Details

Published in:	Marine Drugs
Main Authors:	Unnur Magnusdottir, Yiming Yang Jonatansdottir, Kristinn R. Oskarsson, Jens G. Hjorleifsson, Jon M. Einarsson, Finnbogi R. Thormodsson
Format:	Article
Language:	English
Published:	MDPI AG 2025-09-01
Subjects:	YKL-40 glycosaminoglycans (GAGs) extracellular matrix (ECM) binding affinity Microscale Thermophoresis (MST) molecular docking
Online Access:	https://www.mdpi.com/1660-3397/23/10/379