378 Regulation of renal function by the peroxisome proliferator-activated receptor-alpha: A novel target for treating hypertension

OBJECTIVES/GOALS: Approximately 37 million people in the U.S. have chronic kidney disease, which is a major risk factor for cardiovascular and end stage renal diseases. PPAR-αknockout (KO) mice exhibit increased renal inflammation and blood pressure. In this study, we investigated the role of PPAR-...

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Bibliographic Details

Published in:	Journal of Clinical and Translational Science
Main Authors:	Mark D Hatcher, Kathryn Sandberg, Dexter Lee
Format:	Article
Language:	English
Published:	Cambridge University Press 2023-04-01
Online Access:	https://www.cambridge.org/core/product/identifier/S2059866123004156/type/journal_article