Expression patterns, prognostic significance, and immune correlations of the TNFAIP8 family in acute myeloid leukemia: a comprehensive bioinformatics analysis

Abstract Background Acute myeloid leukemia (AML) is a highly aggressive hematologic malignancy with poor prognosis and high relapse rates. While the TNFAIP8 gene family (TNFAIP8, TNFAIP8L1, TNFAIP8L2, and TNFAIP8L3) is implicated in cancer and immune regulation, its role in AML remains unclear. This...

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Bibliographic Details

Published in:	Discover Oncology
Main Authors:	Xuezhong Zhang, Min Qu, Lei Bi, Xiaolei Wang, Tonggang Liu
Format:	Article
Language:	English
Published:	Springer 2025-05-01
Subjects:	Acute Myeloid Leukemia (AML) TNFAIP8 Family Survival Analysis Receiver Operating Characteristic (ROC) Analysis Biomarkers Functional Analysis
Online Access:	https://doi.org/10.1007/s12672-025-02511-5